منابع مشابه
Chloramphenicol therapy of typhoid fever.
In a prospective study we compared two different dosage regimens of IV chloramphenicol succinate (100 mg/kg/day and 75 mg/kg/day) in children with culture proven typhoid. Trough and peak blood samples, obtained at 48 hrs, were analysed for free chloramphenicol by high pressure liquid chromatography (HPLC). Although the mean trough (8.8 +/- 7.7 versus 5.4 +/- 2.6 mcg/ml) and peak (19.9 +/- 12.2 ...
متن کاملChloramphenicol in Early Diagnosis of Typhoid
the last three and a half years over Ther s have been observed in private practice. reja e has not been a single fatality. Also the usuaN rate has been very much below the figures Wr ,cited (Fairley, 1952). There have been A re^apses only, one relapse in paratyphoid tyoh ̂ ^her in paratyphoid B, yet another in Ga Jp and the last in Bacillus enteritidis Cent sePticemia, a relapse-rate below 2 per...
متن کاملA Case Report "Typhoid Resistant to Chloramphenicol"
Typhoid fever is an infection caused by a strain of bacteria called Salmonella typhi, which is related to the bacteria that causes salmonella food poisoning. The infection can affect the whole body and damage multiple organs. Unless treated, this infection can have life threatening consequences. A 20 year old girl was examined suffering from high fever from one week and abdominal pain for few d...
متن کاملChloramphenicol combined with ampicillin in treatment of typhoid.
Fifty out of 100 patients with typhoid fever, matched for age, stage of illness, and degree of fever, were treated with chloramphenicol and the other 50 were treated with chloramphenicol combined with ampicillin. The febrile period was shortened by up to 29% in patients treated with the combined drugs compared with those given only chloramphenicol. Moreover, no patient on combined therapy had a...
متن کاملManagement of Typhoid Fever and Bacterial Meningitis by Chloramphenicol in Infants and Children
Chloramphenicol inhibits protein synthesis in bacteria and is usually bacteriostatic but is bactericidal against Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitis. Chloramphenicol penetrates all body tissues well. The cerebrospinal fluid concentration averages 60% of the serum level, while brain levels are 9 times higher because of high lipid solubility of this drug. Ch...
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ژورنال
عنوان ژورنال: BMJ
سال: 1972
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.3.5827.645-b